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DSPE-PEG2000-triGalNAc (ammonium)

DSPE-PEG2K-triGalNAc is a polar lipid composed of DSPE and tri-N-acetylgalactosamine that can be used to construct liposomes target to asialoglycoprotein receptor (ASGPR) .

Product Specifications

CAS Number

[2936651-86-2]

UNSPSC

12352211

Target

Liposome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dspe-peg2000-trigalnac-ammonium.html

Purity

99.8

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCCCCCCCCCC(O[C@]([H])(COC(CCCCCCCCCCCCCCCCC)=O)COP(OCCNC(COCCOCC(NCCCCC(N(CC(NCCOCCOCCO[C@H]1O[C@H]([C@H]([C@H]([C@@H]1NC(C)=O)O)O)CO)=O)CC(NCCOCCOCCO[C@H]2O[C@H]([C@H]([C@H]([C@@H]2NC(C)=O)O)O)CO)=O)C(NCCOCCOCCO[C@H]3O[C@H]([C@H]([C@H]([C@@H]3NC(C)=O)O)O)CO)=O)=O)=O)([O-])=O)=O.[NH4+].[n]

Molecular Formula

(C2H4O) nC97H180N9O38P.H3N

Molecular Weight

2000 (Average)

References & Citations

[1]Green Ahn, et al. LYTACs that engage the asialoglycoprotein receptor for targeted protein degradation. Nat Chem Biol. 2021, 17, 9.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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