8-OAc
8-OAc is a potent and selective mitochondrial electron transport chain (ETC) complex I inhibitor. 8-OAc exhibits cytotoxicity against cancer cell lines[1].
Product Specifications
CAS Number
[2550395-87-2]
UNSPSC
12352005
Target
Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-oac.html
Smiles
O=C(NCCC(/C=C\C[C@H](OC(C)=O)C(C)(C)C1=NC(C/C=C\CC=C)=CS1)=C)OC
Molecular Formula
C24H34N2O4S
Molecular Weight
446.60
References & Citations
[1]Naibedya Dutta, et al. Investigating impacts of the mycothiazole chemotype as a chemical probe for the study of mitochondrial function and aging. Geroscience. 2024 Apr 3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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