α-Synuclein inhibitor 10
Product Specifications
UNSPSC Description
α-Synuclein inhibitor 10 (compound a8) inhibits the activity of α-Syn aggregation with low IC50 value (1.08 μM). α-Synuclein inhibitor 10 exhibits good binding affinity to α-Syn residues. α-Synuclein inhibitor 10 can be used in the research of Parkinson's disease (PD)[1].
Target Antigen
α-synuclein
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/α-synuclein-inhibitor-10.html
Solubility
DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(C(C=C1C2=O)=CC(O)=C1C(C3=C2C=CC=C3O)=O)NC4=CC=C(Cl)C=C4O
Molecular Weight
409.78
References & Citations
[1]Wei Zhang, et al. The potential of Rhein's aromatic amines for Parkinson's disease prevention and treatment: α-Synuclein aggregation inhibition and disaggregation of preformed fibers. Bioorg Med Chem Lett. 2024.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-157308/α-Synuclein-inhibitor-10-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-157308/α-Synuclein-inhibitor-10-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
3050715-65-3
Available Sizes
Curated Selection
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