Saikosaponin B3

Saikosaponin B3 is a saikosaponin isolated from the roots of Bupleurum falcatum L., with analgesic effect. Saikosaponin B3 inhibits ACTH-induced lipolysis in the fat cells[1][2][3].

Product Specifications

CAS Number

[58316-42-0]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/saikosaponin-b3.html

Purity

99.54

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@]12[C@@]([C@@H](C=C3[C@]2(C[C@H](O)[C@]4(CO)[C@@]3([H])CC(C)(C)CC4)C)OC)([H])[C@@]5([C@@]([C@@](C)([C@@H](O[C@@]6([H])[C@@H]([C@H]([C@@H](O)[C@@H](C)O6)O[C@]7([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)CO)O)CC5)CO)([H])CC1)C

Molecular Formula

C43H72O14

Molecular Weight

813.02

References & Citations

[1]Jang MJ, et al. Saikosaponin D isolated from Bupleurum falcatum inhibits selectin-mediated cell adhesion. Molecules. 2014 Dec 4;19 (12) :20340-9.|[2]Kita T, et al. Analgesic and other pharmacologic actions of saiko-saponin in repeated cold stressed (SART stressed) animals. J Pharmacobiodyn. 1980 Jun;3 (6) :269-80.|[3]Kimura Y, et al. Effects of saikosaponins on the metabolic actions of adrenaline, ACTH and insulin on the fat cells. Chem Pharm Bull (Tokyo) . 1980 Jun;28 (6) :1788-94.