KDM2B-IN-2
KDM2B-IN-2, a potent histone demethylase (kdm2b) inhibitor with an IC50 of 0.021 μM in a KDM2B TR-FRET assay. KDM2B-IN-2 can be used for hyperproliferative diseases research[1].
Product Specifications
CAS Number
[1965248-01-4]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/kdm2b-in-2.html
Concentration
10mM
Purity
99.36
Solubility
DMSO : 31.25 mg/mL (ultrasonic; heat to 80°C)
Smiles
O=S(C1=CC=C(C2=CSC=C2)C=C1)(N3C(N4CCN(C5CCC5)CC4)=NCC3)=O
Molecular Formula
C21H26N4O2S2
Molecular Weight
430.59
Precautions
H315, H319, H335
References & Citations
[1]Brian K. Albrecht, et al. 4,5-dihydroimidazole derivatives and their use as histone demethylase (kdm2b) inhibitors. Patent WO2016112251A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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