Human CCR4 Full Length Protein (VLP)
C-C chemokine receptor type 4 is a receptor for the following CC chemokines: CCL2, CCL4, CCL5, CCL17, CCL22, belongs to the G protein-coupled receptor family. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. CCR4 is often expressed on leukemic cells in cutaneous T-cell lymphoma (CTCL) . Mogamulizumab is a humanized monoclonal antibody targeted at CCR4and is an investigational drug for CTCL.
Product Specifications
Background
Specifications
This protein .
Accession Number
P51679-1
Expression Region
Met 1 - Leu 360
Host
HEK293
Target
CCR4
Conjugation
Unconjugated
Source
Human
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 12 months under sterile conditions.
Bioactivity
Format
Liquid
Buffer
PBS, Arginine, pH7.4
Additives
Trehalose
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
20ug*1
Host or Source
HEK293
Species
Human
Protein ID
P51679-1
Preservative
Trehalose
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