Penicillin amidase, E. coli

Penicillin amidase (EC 3.5.1.11) (Penicillin acylase) is an enzyme that cleaves the acyl side chains of penicillins. Penicillin amidase can be used for the production of 6-aminopenicillanic acid. Penicillin amidase can also be used in the resolution of racemic mixtures, peptide synthesis, and synthesis of semi-synthetic β-lactam antibiotics[1][2][3].

Product Specifications

CAS Number

[9014-06-6]

Product Name Alternative

PGA

UNSPSC

12352204

Hazard Statement

H334

Target

Biochemical Assay Reagents

Type

Enzyme

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/penicillin-amidase.html

Solubility

10 mM in DMSO

Smiles

[Penicillinamidase,E.coli]

Precautions

H334

References & Citations

[1]Duggleby HJ, et al. Penicillin acylase has a single-amino-acid catalytic centre. Nature. 1995 Jan 19;373 (6511) :264-8. |[2]Avinash VS, et al. Penicillin acylases revisited: importance beyond their industrial utility. Crit Rev Biotechnol. 2016;36 (2) :303-16. |[3]Tishkov VI, et al. Protein engineering of penicillin acylase. Acta Naturae. 2010 Jul;2 (3) :47-61.