Phospho-PLK1 (Thr210) Rabbit FITC Conjugate

<strong>Phospho-PLK1 (Thr210) Rabbit FITC Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018836_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 Tests_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13, STPK13_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Kasahara K, Goto H, Izawa I, Kiyono T, Watanabe N, Elowe S, Nigg EA, Inagaki M. PI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition Nat Commun. 2013;4:1882._x000D_ 2: Tavernier N, Thomas Y, Vigneron S, Maisonneuve P, Orlicky S, Mader P, Regmi SG, Van Hove L, Levinson NM, Gasmi-Seabrook G, Joly N, Poteau M, Velez-Aguilera G, Gavet O, Castro A, Dasso M, Lorca T, Sicheri F, Pintard L. Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry Nat Commun. 2021 Mar 26;12(1):1899._x000D_ 3: Patel JR, Thangavelu P, Terrell RM, Israel B, Sarkar AB, Davidson AM, Zhang K, Khupse R, Tilghman SL. A Novel Allosteric Inhibitor Targets PLK1 in Triple Negative Breast Cancer Cells Biomolecules. 2022 Mar 31;12(4):531._x000D_ 4: van de Weerdt BC, van Vugt MA, Lindon C, Kauw JJ, Rozendaal MJ, Klompmaker R, Wolthuis RM, Medema RH. Uncoupling anaphase-promoting complex/cyclosome activity from spindle assembly checkpoint control by deregulating polo-like kinase 1 Mol Cell Biol. 2005 Mar;25(5):2031-44._x000D_ 5: Du J, Cao Y, Wang Q, Zhang N, Liu X, Chen D, Liu X, Xu Q, Ma W. Unique subcellular distribution of phosphorylated Plk1 (Ser137 and Thr210) in mouse oocytes during meiotic division and pPlk1(Ser137) involvement in spindle formation and REC8 cleavage Cell Cycle. 2015;14(22):3566-79._x000D_ 6: Kamakura N, Takahashi M, Jo M. The toxicity of dysregulated Plk1 activity revealed by its suppressor mutations Genes Cells. 2023 Jul;28(7):503-515._x000D_ 7: Shao H, Huang Y, Zhang L, Yuan K, Chu Y, Dou Z, Jin C, Garcia-Barrio M, Liu X, Yao X. Spatiotemporal dynamics of Aurora B-PLK1-MCAK signaling axis orchestrates kinetochore bi-orientation and faithful chromosome segregation Sci Rep. 2015 Jul 24;5:12204._x000D_ 8: Wu B, Jiang P, Mu Y, Wilmouth RC. Cancer Osaka thyroid (Cot) phosphorylates Polo-like kinase (PLK1) at Ser137 but not at Thr210 Biol Chem. 2009 Dec;390(12):1271-7._x000D_ 9: Jiang S, Tang DD. Plk1 regulates MEK1/2 and proliferation in airway smooth muscle cells Respir Res. 2015 Aug 5;16(1):93._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/26114227">10: Chou CH, Loh JK, Yang MC, Lin CC, Hong MC, Cho CL, Chou AK, Wang CH, Lieu AS, Howng SL, Hsu CM, Hong YR. AIBp regulates mitotic entry and mitotic spindle assembly by controlling activation of both Aurora-A and Plk1 Cell Cycle. 2015;14(17):2764-76. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-PLK1 (Thr210) Rabbit FITC Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Conjugates/"> Conjugates</a>