BB-Cl-Amidine (hydrochloride)
BB-Cl-Amidine hydrochloride is a peptidylarginine deminase (PAD) inhibitor[1].
Product Specifications
CAS Number
[2436747-41-8]
UNSPSC
12352005
Target
Protein Arginine Deiminase
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bb-cl-amidine-hydrochloride.html
Purity
99.47
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC=C(C2=CC=CC=C2)C=C1)N[C@H](C3=NC4=CC=CC=C4N3)CCCNC(CCl)=N.Cl
Molecular Formula
C26H27Cl2N5O
Molecular Weight
496.43
References & Citations
[1]Knight JS, et al. Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice. Ann Rheum Dis. 2015 Dec;74 (12) :2199-206.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Citation 01
Acta Neuropathol Commun. 2025 Feb 18;13 (1) :33.|Adv Sci (Weinh) . 2025 Aug 20:e11873.|Mol Med. 2025 Feb 5;31 (1) :46.|Nat Cell Biol. 2021 Oct;23 (10) :1060-1072.|Nat Commun. 2024 Sep 3;15 (1) :7654.|Oncol Rep. 2023 Jul;50 (1) :146.|Res Sq. 2024 Jun 04.|Cell Physiol Biochem. 2024 Feb 19;58 (1) :63-82.|Int Immunopharmacol. 2024 Nov 5;143 (Pt 3) :113534.|J Antibiot (Tokyo) . 2025 Oct 9.
Available Sizes
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