PARP-1/2/7-IN-1
PARP-1/2/7-IN-1 (compound 86) is a potent inhibitor of PARP-1/2/7, with the IC50 of [1].
Product Specifications
CAS Number
3034665-49-8
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/parp-1-2-7-in-1.html
Smiles
O=C1NN=C2C(CC[C@H]2N3C[C@H](C(N4CCN(C5=NC=C(C(F)(F)F)C=N5)CC4)=O)OCC3)=C1C(F)(F)F
Molecular Formula
C22H23F6N7O3
Molecular Weight
547.45
References & Citations
[1]Azkarra Therapeutics, Inc.; Oregon Health, et al. Preparation of pyridazin-3 (2H) -one and pyridin-2 (1H) -one PARP inhibitor compounds. World Intellectual Property Organization, WO2024073133 A1 2024-04-04
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP1; PARP2; PARP7
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