Pomalidomide-C6-O-C5-O-C4-COOH
Pomalidomide-C6-O-C5-O-C4-COOH is a E3 ligase ligand-linker conjugate comprising a Pomalidomide (HY-10984) -based cereblon ligand and linker. Pomalidomide-C6-O-C5-O-C4-COOH can be used for the synthesis of PROTACs[1].
Product Specifications
CAS Number
[2375774-54-0]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-c6-o-c5-o-c4-cooh.html
Purity
98.55
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)CCCCOCCCCCOCCCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Molecular Formula
C29H41N3O8
Molecular Weight
559.65
References & Citations
[1]Steinebach C , et al. PROTAC-mediated crosstalk between E3 ligases. Chem Commun (Camb) . 2019 Feb 5;55 (12) :1821-1824.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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