4,4'-Dicyanostilbene

4,4'-Dicyanostilbene (compound 43) is a potent antimalarial agent against the Dd2 strain, with an EC50 of 27 nM. 4,4'-Dicyanostilbene exhibits in vivo efficacy against methicillin-resistant Staphylococcus aureus (MRSA) [1].

Product Specifications

CAS Number

[5216-37-5]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/4-4-dicyanostilbene.html

Solubility

10 mM in DMSO

Smiles

N#CC1=CC=C(/C=C/C2=CC=C(C=C2)C#N)C=C1

Molecular Formula

C16H10N2

Molecular Weight

230.26

References & Citations

[1]Kyei-Baffour K, et, al. Natural product-inspired aryl isonitriles as a new class of antimalarial compounds against drug-resistant parasites. Bioorg Med Chem. 2020 Oct 1;28 (19) :115678.