Altertoxin I

Altertoxin I (Dihydroalterperylenol) is a quinone-type mycotoxin produced by Alternaria alternata fungi, which is mutagenic and cytotoxic, and can weakly disrupts metabolic communication[1].

Product Specifications

CAS Number

[56258-32-3]

Product Name Alternative

Dihydroalterperylenol

UNSPSC

12352005

Hazard Statement

H301, H311, H331

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/altertoxin-i.html

Purity

99.65

Solubility

10 mM in DMSO

Smiles

O=C(C1=C2C3=CC=C1O)CC[C@]2([C@@]([H])(C4=C3C=CC(O)=C45)[C@H](CC5=O)O)O

Molecular Formula

C20H16O6

Molecular Weight

352.34

Precautions

H301, H311, H331

References & Citations

[2]Boutin BK, et al. Effects of purified altertoxins I, II, and III in the metabolic communication V79 system. J Toxicol Environ Health. 1989;26 (1) :75-81.|[3]Stack ME, et al. Mutagenicity of the Alternaria metabolites altertoxins I, II, and III. Appl Environ Microbiol. 1986 Oct;52 (4) :718-22.|[1]Jarolim K, et al. Activation of the Nrf2-ARE pathway by the Alternaria alternata mycotoxins altertoxin I and II. Arch Toxicol. 2017 Jan;91 (1) :203-216.