2-(2,6-Dioxopiperidin-3-yl)phthalimidine
Product Specifications
UNSPSC Description
2-(2,6-Dioxopiperidin-3-yl)phthalimidine (EM-12), a teratogenic Thalidomide analogue, is more active than Thalidomide and is much more stable for hydrolysis. 2-(2,6-Dioxopiperidin-3-yl)phthalimidine enhances 1,2-dimethylhydrazine-induction of rat colon adenocarcinomas[1][2].
Target Antigen
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-2-6-dioxopiperidin-3-yl-phthalimidine.html
Smiles
O=C(C(N(CC1=C2C=CC=C1)C2=O)CC3)NC3=O
Molecular Weight
244.25
References & Citations
[1]Merker HJ, et al. Embryotoxic effects of thalidomide-derivatives in the non-human primate Callithrix jacchus. I. Effects of 3-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-dioxopiperidine (EM12) on skeletal development. Arch Toxicol. 1988;61(3):165-179.|[2]Gershbein LL. The thalidomide analog, EM 12, enhances 1,2-dimethylhydrazine-induction of rat colon adenocarcinomas. Cancer Lett. 1991;60(2):129-133.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-138793/2-2-6-Dioxopiperidin-3-yl-phthalimidine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-138793/2-2-6-Dioxopiperidin-3-yl-phthalimidine-SDS-MedChemExpress.pdf
CAS Number
26581-81-7
Available Sizes
Curated Selection
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