Decoyinine
Decoyinine is a selective inhibitor of GMP synthetase (GMPS) .
Product Specifications
CAS Number
[2004-04-8]
Product Name Alternative
Angustmycin A
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Cyclic GMP-AMP Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Decoyinine.html
Concentration
10mM
Purity
99.96
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C=C(O1)[C@@H](O)[C@@H](O)[C@]1(CO)N2C=NC3=C(N)N=CN=C32
Molecular Formula
C11H13N5O4
Molecular Weight
279.25
Precautions
H315, H319, H335
References & Citations
[1]A Bianchi-Smiraglia, et al. Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity. Cell Death Differ. 2015 Nov; 22 (11) : 1858–1864.|[2]W L Nicholson, et al. Effect of Decoyinine on the regulation of alpha-amylase synthesis in Bacillus subtilis. J Bacteriol. 1987 Dec; 169 (12) : 5867–5869.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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