Decoyinine

Decoyinine is a selective inhibitor of GMP synthetase (GMPS) .

Product Specifications

CAS Number

[2004-04-8]

Product Name Alternative

Angustmycin A

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Cyclic GMP-AMP Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Decoyinine.html

Concentration

10mM

Purity

99.96

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C=C(O1)[C@@H](O)[C@@H](O)[C@]1(CO)N2C=NC3=C(N)N=CN=C32

Molecular Formula

C11H13N5O4

Molecular Weight

279.25

Precautions

H315, H319, H335

References & Citations

[1]A Bianchi-Smiraglia, et al. Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity. Cell Death Differ. 2015 Nov; 22 (11) : 1858–1864.|[2]W L Nicholson, et al. Effect of Decoyinine on the regulation of alpha-amylase synthesis in Bacillus subtilis. J Bacteriol. 1987 Dec; 169 (12) : 5867–5869.