α-Synuclein (45-54) (human)

α-Synuclein (45-54) (human) is the 45-54 fragment of α-Synuclein. α-Synuclein is an abundant neuronal protein that is highly abundant in presynaptic nerve terminals. α-Synuclein is a biomarker for Parkinson's disease (PD) [1].

Product Specifications

CAS Number

[2243206-98-4]

UNSPSC

12352209

Target

α-synuclein

Type

Peptides

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/α-synuclein-45-54-human.html

Solubility

10 mM in DMSO

Smiles

NCCCC[C@H](N)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@H](C(NCC(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@H](C(O)=O)[C@H](O)C)=O)=O)=O)=O)CC1=CN=CN1)=O)=O)=O)=O)=O

Molecular Formula

C43H73N13O14

Molecular Weight

996.12

References & Citations

[1]Cheruvara H, et al. Intracellular screening of a peptide library to derive a potent peptide inhibitor of α-synuclein aggregation. J Biol Chem. 2015 Mar 20;290 (12) :7426-35.