L-Leucine-18O2
L-Leucine-18O2 is the 18O-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
Product Specifications
CAS Number
[73579-45-0]
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Endogenous Metabolite; Isotope-Labeled Compounds; mTOR
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-leucine-18o2.html
Purity
98
Solubility
10 mM in DMSO
Smiles
CC(C)C[C@H](N)C([18OH])=[18O]
Molecular Formula
C6H13N 18O2
Molecular Weight
135.17
Precautions
H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
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