STIP1/HOP Rabbit pAb
STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]). [supplied by OMIM, Jul 2009],
Product Specifications
Background
Product Name Alternative
UniProt
P31948
Swiss Prot
P31948
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human STIP1/HOP AA range: 250-300
Target
STIP1/HOP
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; WB
Concentration
1 mg/ml
Dilution
IHC-p1:50-200 , WB 1:1000-2000
Buffer
-20°C/1 year
Molecular Weight
64kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
64kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Dynein axonemal particle .
Other Product Names
Gene ID (Human)
10963
Available Sizes
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