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Mutated EGFR-IN-1

Mutated EGFR-IN-1 (Osimertinib analog) (Intermediate 168) is an intermediate of the mutant EGFR inhibitor.

Product Specifications

CAS Number

1421372-66-8

Product Name Alternative

Osimertinib analog

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mutated-egfr-in-1.html

Concentration

10mM

Purity

99.90

Solubility

DMSO : ≥ 75 mg/mL

Smiles

NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C

Molecular Formula

C25H31N7O

Molecular Weight

445.56

Precautions

H302, H315, H319, H335

References & Citations

[1]Patent WO 2013014448 A1. 2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer
 .

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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