Mutated EGFR-IN-1
Mutated EGFR-IN-1 (Osimertinib analog) (Intermediate 168) is an intermediate of the mutant EGFR inhibitor.
Product Specifications
CAS Number
[1421372-66-8]
Product Name Alternative
Osimertinib analog
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mutated-egfr-in-1.html
Concentration
10mM
Purity
99.90
Solubility
DMSO : ≥ 75 mg/mL
Smiles
NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C
Molecular Formula
C25H31N7O
Molecular Weight
445.56
Precautions
H302, H315, H319, H335
References & Citations
[1]Patent WO 2013014448 A1. 2 - (2, 4, 5 - substituted -anilino) pyrimidine derivatives as egfr modulators useful for treating cancer
 .
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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