HMAO-B-IN-5

HMAO-B-IN-5 (Compound B15) is a potent, selective and reversible human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 of 120 nM and a Ki of 33 nM. hMAO-B-IN-5 can be used in the research of neurodegenerative diseases[1].

Product Specifications

CAS Number

[358343-63-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hmao-b-in-5.html

Purity

99.66

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC=C(OCC)C=C1)/C=C/C2=CC=C(OCC3=CC=CC=C3)C=C2

Molecular Formula

C24H22O3

Molecular Weight

358.43

Precautions

H302, H315, H319

References & Citations

[1]Sachithra Thazhathuveedu Sudevan, et al. Introduction of benzyloxy pharmacophore into aryl/heteroaryl chalcone motifs as a new class of monoamine oxidase B inhibitors. Sci Rep. 2022 Dec 27;12 (1) :22404.