Aminopotentidine
Aminopotentidine is a histamine H2 receptor antagonist with KB values of 220 nM and 280 nM for human and guinea pig H2 receptors, respectively. It can also serve as a precursor for the synthesis of [125I] iodo derivatives[1].
Product Specifications
CAS Number
[140873-26-3]
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/aminopotentidine.html
Purity
98.54
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NCCN/C(NC#N)=N/CCCOC1=CC=CC(CN2CCCCC2)=C1)C3=CC=C(N)C=C3
Molecular Formula
C26H35N7O2
Molecular Weight
477.60
References & Citations
[1]Hirschfeld J, et al. Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H2 receptor[J]. Journal of medicinal chemistry, 1992, 35 (12) : 2231-2238.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H2 Receptor
Available Sizes
Curated Selection
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