Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside

Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside (pNP-G7) is the substrate of α-amylase. Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside is degraded by amylase in the presence of auxiliary enzymes (such as α-glucosidase) to release the chromophore, allowing the measurement of amylase activity. Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside can be used for the diagnosis of pancreatitis[1][2].

Product Specifications

CAS Number

[96597-16-9]

Product Name Alternative

PNP-G7

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Amylases

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ethylidene-4-nitrophenyl-a-d-maltoheptaoside.html

Purity

99.42

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)O[C@H](O[C@@H]4[C@@H](CO)O[C@H](O[C@@H]5[C@@H](CO)O[C@H](O[C@@H]6[C@@H](CO)O[C@H](O[C@@H]7[C@@H](CO)O[C@H](OC8=CC=C([N+]([O-])=O)C=C8)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O)[C@H](O)[C@H]5O)[C@H](O)[C@H]4O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)O[C@H]9[C@@H](OC(C)OC9)[C@@H]1O

Molecular Formula

C50H77NO38

Molecular Weight

1300.13

Precautions

H302, H315, H319, H335

References & Citations

[1]Lorentz K. Routine alpha-amylase assay using protected 4-nitrophenyl-1, 4-alpha-D-maltoheptaoside and a novel alpha-glucosidase. Clin Chem. 2000 May;46 (5) :644-9.|[2]Cobbaert C. Discrepancies between methods for amylase in cases of macroamylasemia. Clinical chemistry, 1991, 37 (12) : 2159-2160.