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BAD (103-127) (human), FAM-labeled

BAD (103-127) (human), FAM-labeled is a FAM-labeled human BAD (103-127). BAD (103-127) (human), the 25-mer Bad peptide, is derived from the BH3 domain of BAD and can antagonize the function of Bcl-xL[1].

Product Specifications

UNSPSC

12352209

Target

Bcl-2 Family

Type

Peptides

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bad-103-127-human-fam-labeled.html

Solubility

10 mM in DMSO

Smiles

OC1=CC2=C(C3(C4=C(O2)C=C(O)C=C4)C5=C(C(O3)=O)C=C(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)CCCCN)=O)CC6=CC=CC=C6)=O)CO)=O)CC(O)=O)=O)C(C)C)=O)CC7=CC=CC=C7)=O)CCC(O)=O)=O)CC(O)=O)=O)CO)=O)CCSC)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CC(C)C)=O)CCC(O)=O)=O)CCCNC(N)=N)=O)=O)CC8=CC=C(O)C=C8)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)C)=O)C)=O)CC9=CNC%10=CC=CC=C9%10)=O)CC(C)C)=O)CC(N)=O)=O)C=C5)C=C1

Molecular Formula

C158H222N42O45S

Molecular Weight

3461.80

References & Citations

[1]Dilraj Lama, et al. Molecular dynamics simulations of pro-apoptotic BH3 peptide helices in aqueous medium: relationship between helix stability and their binding affinities to the anti-apoptotic protein Bcl-X (L) . J Comput Aided Mol Des. 2011 May;25 (5) :413-26.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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