BAD (103-127) (human), FAM-labeled
BAD (103-127) (human), FAM-labeled is a FAM-labeled human BAD (103-127). BAD (103-127) (human), the 25-mer Bad peptide, is derived from the BH3 domain of BAD and can antagonize the function of Bcl-xL[1].
Product Specifications
UNSPSC
12352209
Target
Bcl-2 Family
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bad-103-127-human-fam-labeled.html
Solubility
10 mM in DMSO
Smiles
OC1=CC2=C(C3(C4=C(O2)C=C(O)C=C4)C5=C(C(O3)=O)C=C(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)CCCCN)=O)CC6=CC=CC=C6)=O)CO)=O)CC(O)=O)=O)C(C)C)=O)CC7=CC=CC=C7)=O)CCC(O)=O)=O)CC(O)=O)=O)CO)=O)CCSC)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CC(C)C)=O)CCC(O)=O)=O)CCCNC(N)=N)=O)=O)CC8=CC=C(O)C=C8)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)C)=O)C)=O)CC9=CNC%10=CC=CC=C9%10)=O)CC(C)C)=O)CC(N)=O)=O)C=C5)C=C1
Molecular Formula
C158H222N42O45S
Molecular Weight
3461.80
References & Citations
[1]Dilraj Lama, et al. Molecular dynamics simulations of pro-apoptotic BH3 peptide helices in aqueous medium: relationship between helix stability and their binding affinities to the anti-apoptotic protein Bcl-X (L) . J Comput Aided Mol Des. 2011 May;25 (5) :413-26.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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