Emodepside
Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity.
Product Specifications
CAS Number
155030-63-0
Product Name Alternative
Bay 44-4400
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Emodepside.html
Purity
98.42
Solubility
DMSO : 120 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
O=C(N([C@H](C(O[C@](C(N([C@H](C(O[C@H](CC1=CC=C(N2CCOCC2)C=C1)C(N(C)[C@H](CC(C)C)C(O[C@H](C)C(N(C)[C@@H](CC(C)C)C3=O)=O)=O)=O)=O)CC(C)C)C)=O)([H])C)=O)CC(C)C)C)[C@H](O3)CC4=CC=C(N5CCOCC5)C=C4
Molecular Formula
C60H90N6O14
Molecular Weight
1119.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Harder A, et al. Mechanisms of action of emodepside. Parasitol Res. 2005 Oct;97 Suppl 1:S1-10.|[2]Buxton SK, et al. On the mode of action of emodepside: slow effects on membrane potential and voltage-activated currents in Ascaris suum. Br J Pharmacol. 2011 Sep;164 (2b) :453-70.|[3]Kulke D, et al. Characterization of the Ca2+-gated and voltage-dependent K+-channel Slo-1 of nematodes and its interaction with emodepside. PLoS Negl Trop Dis. 2014 Dec 18;8 (12) :e3401.|[4]Bull K, et al. Effects of the novel anthelmintic emodepside on the locomotion, egg-laying behaviour and development of Caenorhabditis elegans. Int J Parasitol. 2007 May;37 (6) :627-36.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC680226-100 1x 100 µL
Pmel17 / gp100 / SILV (NKI-beteb), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940181-100 1x 100 µL
CD59 (heavy chain of Protectin) (BRA-10G), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400460-100 1x 100 µL
CD44 Standard (156-3C11), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040096-100 1x 100 µL
Histone H1 (AE-4), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details