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PLK4-IN-4

PLK4-IN-4 (compound 22) is a potent PLK4 inhibitor with an IC50 value of 7.9 nM. PLK4-IN-4 has the potential for the research of cancer[1].

Product Specifications

CAS Number

[2923999-01-1]

UNSPSC

12352005

Target

Polo-like Kinase (PLK)

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/plk4-in-4.html

Purity

99.89

Solubility

10 mM in DMSO

Smiles

CC1=CC(NC2=C3C(N(C4CCNCC4)N=C3)=NC(NCC5=CC=C(F)C=C5F)=N2)=NN1

Molecular Formula

C21H23F2N9

Molecular Weight

439.46

References & Citations

[1]DongMei Zhao, et al. Pyrazolopyrimidine derivative, and preparation method and application thereof. CN116023380A.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-128493/PLK4-IN-4-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-128493/PLK4-IN-4-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PLK4

Available Sizes

Curated Selection

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