PLK4-IN-4

PLK4-IN-4 (compound 22) is a potent PLK4 inhibitor with an IC50 value of 7.9 nM. PLK4-IN-4 has the potential for the research of cancer[1].

Polo-like Kinase (PLK)

Reference compound

Cell Cycle/DNA Damage

Cancer

https://www.medchemexpress.com/plk4-in-4.html

99.89

10 mM in DMSO

CC1=CC(NC2=C3C(N(C4CCNCC4)N=C3)=NC(NCC5=CC=C(F)C=C5F)=N2)=NN1

439.46

[1]DongMei Zhao, et al. Pyrazolopyrimidine derivative, and preparation method and application thereof. CN116023380A.

Room Temperature

4°C (Powder, protect from light)

http://file.medchemexpress.com/batch_PDF/HY-128493/PLK4-IN-4-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-128493/PLK4-IN-4-SDS-MedChemExpress.pdf

No Development Reported

2923999-01-1