PLK4-IN-4
PLK4-IN-4 (compound 22) is a potent PLK4 inhibitor with an IC50 value of 7.9 nM. PLK4-IN-4 has the potential for the research of cancer[1].
Product Specifications
CAS Number
[2923999-01-1]
UNSPSC
12352005
Target
Polo-like Kinase (PLK)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plk4-in-4.html
Purity
99.89
Solubility
10 mM in DMSO
Smiles
CC1=CC(NC2=C3C(N(C4CCNCC4)N=C3)=NC(NCC5=CC=C(F)C=C5F)=N2)=NN1
Molecular Formula
C21H23F2N9
Molecular Weight
439.46
References & Citations
[1]DongMei Zhao, et al. Pyrazolopyrimidine derivative, and preparation method and application thereof. CN116023380A.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PLK4
Available Sizes
Curated Selection
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