Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

ABBV-318

ABBV-318 is a potent Nav1.7/ Nav1.8 blocker, with IC50s of 2.8 μM and 3.8 μM for hNav1.7 and hNav1.8, respectively. ABBV-318 can be used for the research of pain[1].

Product Specifications

CAS Number

1802848-94-7

UNSPSC

12352005

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/abbv-318.html

Concentration

10mM

Purity

98.72

Solubility

DMSO : 166.67 mg/mL (ultrasonic)

Smiles

O=C(N1C[C@H](F)CC1)C2=NC3=CC=C(OC4=NC=C(C(F)(F)F)C=C4)C=C3C=C2

Molecular Formula

C20H15F4N3O2

Molecular Weight

405.35

References & Citations

[1]Patel MV, et, al. Discovery of (R) - (3-fluoropyrrolidin-1-yl) (6- ((5- (trifluoromethyl) pyridin-2-yl) oxy) quinolin-2-yl) methanone (ABBV-318) and analogs as small molecule Na v 1.7/ Nav1.8 blockers for the treatment of pain. Bioorg Med Chem. 2022 Jun 1;63:116743.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Nav1.7; Nav1.8

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Pantothenic Acid (Technical Grade, Contains Lactone)
TRC-P190305-250MG 250 mg

Pantothenic Acid (Technical Grade, Contains Lactone)

Sign In for Pricing
View Details
Frozen Tissue Sections, Duodenum
CS632781 5x 5 µm

Frozen Tissue Sections, Duodenum

Sign In for Pricing
View Details
Tle3 Mouse Gene Knockout Kit (CRISPR)
KN517612 1 Kit

Tle3 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
Cyclic AMP Direct Chemiluminescent ELISA Kit
K019-C5 5 Plates

Cyclic AMP Direct Chemiluminescent ELISA Kit

Sign In for Pricing
View Details
UBE2S Mouse Monoclonal Antibody [Clone ID: AT2C12]
AM09138PU-N 100 µL

UBE2S Mouse Monoclonal Antibody [Clone ID: AT2C12]

Sign In for Pricing
View Details
N6-Benzoyl-7’-OH-N-trityl morpholino adenine N-Dimer
TRC-B790160-25MG 25 mg

N6-Benzoyl-7’-OH-N-trityl morpholino adenine N-Dimer

Sign In for Pricing
View Details