LSD1-IN-30
LSD1-IN-30 (compound 3) is a potent inhibitor of lysine-specific demethylase 1 (LSD1), with the IC50 value of 0.291 μM[1].
Product Specifications
CAS Number
[1289575-45-6]
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lsd1-in-30.html
Purity
99.03
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C=C1)O)N/N=C(C2=C(C=CC=C2)O)\C
Molecular Formula
C15H14N2O3
Molecular Weight
270.28
References & Citations
[1]Venkataswamy Sorna, et al. High-Throughput Virtual Screening Identifies Novel N′‑ (1-Phenylethylidene) -benzohydrazides as Potent, Specific, and Reversible LSD1 Inhibitors. J Med Chem . 2013 Dec 12;56 (23) :9496-508.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM1/LSD1
Available Sizes
Curated Selection
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