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Patuletin

Patuletin is a flavonol, that can be isolated from the flowers of Tagetes patula. Patuletin shows anti-proliferative activity against cancer cells. Patuletin causes significant nuclear fragmentation and has a great capacity to induce caspase-3 activation[1][2].

Product Specifications

CAS Number

[519-96-0]

UNSPSC

12352005

Target

Apoptosis; Caspase

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/patuletin.html

Solubility

10 mM in DMSO

Smiles

O=C1C(O)=C(C2=CC(O)=C(O)C=C2)OC3=CC(O)=C(C(O)=C13)OC

Molecular Formula

C16H12O8

Molecular Weight

332.26

References & Citations

[1]Zane A , et al. Flavonols in Spinach Leaves[J]. Journal of Organic Chemistry, 1961, 26 (11) .|[2]Alvarado-Sansininea JJ, et al. Quercetagetin and Patuletin: Antiproliferative, Necrotic and Apoptotic Activity in Tumor Cell Lines. Molecules. 2018 Oct 9;23 (10) :2579.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N12503/Patuletin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N12503/

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Caspase 3

Available Sizes

Curated Selection

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