Patuletin
Patuletin is a flavonol, that can be isolated from the flowers of Tagetes patula. Patuletin shows anti-proliferative activity against cancer cells. Patuletin causes significant nuclear fragmentation and has a great capacity to induce caspase-3 activation[1][2].
Product Specifications
CAS Number
519-96-0
UNSPSC
12352005
Target
Apoptosis; Caspase
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/patuletin.html
Solubility
10 mM in DMSO
Smiles
O=C1C(O)=C(C2=CC(O)=C(O)C=C2)OC3=CC(O)=C(C(O)=C13)OC
Molecular Formula
C16H12O8
Molecular Weight
332.26
References & Citations
[1]Zane A , et al. Flavonols in Spinach Leaves[J]. Journal of Organic Chemistry, 1961, 26 (11) .|[2]Alvarado-Sansininea JJ, et al. Quercetagetin and Patuletin: Antiproliferative, Necrotic and Apoptotic Activity in Tumor Cell Lines. Molecules. 2018 Oct 9;23 (10) :2579.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Caspase 3
Available Sizes
Frequently Asked Questions
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