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(rac) -NDT-19795

(rac) -NDT-19795 is the racemate of NDT-19795. NDT-19795 is a potent inhibitor of the NLRP3 inflammasome, demonstrating an IC50 of 66 nM in the PBMC assay and 4.7 μM in the WB assay. This compound is a carboxylic acid active substance, which can be intracellularly converted from NT-0796. NDT-19795 is applicable in studies related to inflammatory and neurological disorders.

Product Specifications

CAS Number

2272918-42-8

Smiles

O=C (OC (C (=O) O) CC1=NC=CC=N1) NC=2C3=C (C=C4C2CCC4) CCC3

Molecular Formula

C20H21N3O4

Molecular Weight

367.41

Notes

For research use only.

Available Sizes

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