Myricetin

Myricetin is a common plant-derived flavonoid with a wide range of activities including strong anti-oxidant, anticancer, antidiabetic and anti-inflammatory activities.

Product Specifications

CAS Number

[529-44-2]

Product Name Alternative

Cannabiscetin

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Autophagy; Endogenous Metabolite; PI3K

Type

Natural Products

Related Pathways

Apoptosis; Autophagy; Metabolic Enzyme/Protease; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Myricetin.html

Concentration

10mM

Purity

98.80

Solubility

DMSO : ≥ 31 mg/mL|Ethanol : 28.57 mg/mL (ultrasonic)

Smiles

OC1=CC(O)=C(C(C(O)=C(C2=CC(O)=C(O)C(O)=C2)O3)=O)C3=C1

Molecular Formula

C15H10O8

Molecular Weight

318.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Semwal DK, et al. Myricetin: A Dietary Molecule with Diverse Biological Activities. Nutrients. 2016 Feb 16;8 (2) :90.|[2]Phillips PA, et al. Myricetin induces pancreatic cancer cell death via the induction of apoptosis and inhibition of thephosphatidylinositol 3-kinase (PI3K) signaling pathway. Cancer Lett. 2011 Sep 28;308 (2) :181-8.|[3]Xu Y, et al. Myricetin induces apoptosis via endoplasmic reticulum stress and DNA double-strand breaks in human ovarian cancer cells. Mol Med Rep. 2016 Mar;13 (3) :2094-100.|[4]Jinwal UK, et al. Chemical Manipulation of Hsp70 ATPase Activity Regulates Tau Stability. J Neurosci. 2009 Sep 30;29 (39) :12079-88.|[5]Tzeng SH, et al. Inhibition of platelet aggregation by some flavonoids. Thromb Res. 1991 Oct 1;64 (1) :91-100.