Neu5Ac-2Galβ1-3Glc-oxazoline- (2) Me
Neu5Ac-2Galβ1-3Glc-oxazoline- (2) Me (Compound G12) is a disaccharide linker effectively recognized by the glycosidase Endo-S2. It can be selectively transferred to the conserved N-glycosylation site (Asn297) of the Fc domain of antibodies through an enzyme-catalyzed reaction, enabling site-specific modification of antibodies. This compound is useful in synthesizing antibody-drug conjugates (ADCs) .
Product Specifications
CAS Number
2823367-76-4
Smiles
O (C[C@H]1O[C@@H] (O[C@@H]2[C@@H] (CO) O[C@]3 ([C@@] ([C@H]2O) (N=C (C) O3) [H]) [H]) [C@H] (O) [C@@H] (O) [C@H]1O) [C@@]4 (C (O) =O) O[C@@] ([C@@H] ([C@@H] (CO) O) O) ([C@H] (NC (C) =O) [C@@H] (O) C4) [H]
Molecular Formula
C25H40N2O18
Molecular Weight
656.59
Notes
For research use only.
Available Sizes
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