Streptokinase, Streptococcus hemolyticus

Streptokinase, an enzyme from Streptococcus hemolyticus (EC 3.4.99.0), is secreted by various streptococci. It binds to and activates human plasminogen. The complex formed between streptokinase and human plasminogen can activate additional unbound plasminogen by cleaving specific bonds, resulting in the production of plasmin.