β-Hydroxybutyrate Dehydrogenase, Pseudomonas lemoignei

β-Hydroxybutyrate Dehydrogenase, Pseudomonas lemoignei (EC 1.1.1.30) is a soluble cytosolic enzyme that does not require phospholipid allosteric activators. It is essential for utilizing ketone bodies as a source of metabolic energy, catalyzing the oxidation of 3-hydroxybutyrate to acetoacetate. This reaction marks the initial step in the conversion of ketone bodies to citric acid, which is subsequently metabolized through the tricarboxylic acid cycle (Krebs cycle) .