(-) -Aspartic acid
(-) -Aspartic acid is a pyroptosis inhibitor. (-) -Aspartic acid acts as a neurotransmitter and neuromodulator, participates in hormone synthesis and regulation, and plays a role in nervous system development and endocrine system[5].
Product Specifications
CAS Number
1783-96-6
Product Name Alternative
(R) -Aspartic acid; D- (-) -Aspartic acid
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Pyroptosis
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/_-_-Aspartic_acid.html
Purity
98.0
Solubility
DMSO : < 1 mg/mL|H2O : 66.67 mg/mL (ultrasonic; adjust pH to 7 with 1M NaOH)
Smiles
N[C@@H](C(O)=O)CC(O)=O
Molecular Formula
C4H7NO4
Molecular Weight
133.10
Precautions
H302, H315, H319, H335
References & Citations
[1]Xuechun Du, et al. D-aspartic acid protects against gingival fbroblasts infammation by suppressing pyroptosis. Mol Biol Rep. 2022 Jul;49 (7) :5821-5829.|[2]Di Nisio A, et al. D-Aspartic acid stimulates steroidogenesis through the delay of LH receptor internalization in a mammalian Leydig cell line. J Endocrinol Invest. 2016 Feb;39 (2) :207-213. |[3]D'Aniello A, et al. Involvement of D-aspartic acid in the synthesis of testosterone in rat testes. Life Sci. 1996;59 (2) :97-104. |[4]D'Aniello A, et al. Occurrence of D-aspartic acid and N-methyl-D-aspartic acid in rat neuroendocrine tissues and their role in the modulation of luteinizing hormone and growth hormone release. FASEB J. 2000 Apr;14 (5) :699-714. |[5]D'Aniello A. D-Aspartic acid: an endogenous amino acid with an important neuroendocrine role. Brain Res Rev. 2007 Feb;53 (2) :215-34.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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