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Fmoc-Val-Cit-PAB-Exatecan

Fmoc-Val-Cit-PAB-Exatecan is a prodrug form of Exatecan. Exatecan (DX-8951) acts as an inhibitor of DNA topoisomerase I (topoisomerase I) with an IC50 value of 2.2 μM (0.975 μg/mL) and is utilized in cancer research.

Product Specifications

CAS Number

2754384-69-3

Smiles

N (C (OCC1=CC=C (NC ([C@@H] (NC ([C@@H] (NC (OCC2C=3C (C=4C2=CC=CC4) =CC=CC3) =O) [C@H] (C) C) =O) CCCNC (N) =O) =O) C=C1) =O) [C@@H]5C6=C7C (C=8N (C7) C (=O) C9=C (C8) [C@] (CC) (O) C (=O) OC9) =NC=%10C6=C (CC5) C (C) =C (F) C%10

Molecular Formula

C58H59FN8O11

Molecular Weight

1063.15

Notes

For research use only.

Available Sizes

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