CM-1758
CM-1758 is a histone deacetylase (HDAC) inhibitor. CM-1758 inhibits tumor growth in vivo. CM-1758 induces acetylation of non-histone proteins in acute myeloid leukemia cells[1].
Product Specifications
CAS Number
2256079-39-5
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cm-1758.html
Purity
98.44
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NO)C1=CN=C(N2CCC(CNC3=CC(C4=C(C)OC(C)=C4)=NC5=CC(OC)=C(OC)C=C53)CC2)N=C1
Molecular Formula
C28H32N6O5
Molecular Weight
532.59
References & Citations
[1]José-Enériz ES, et al. Novel epigenetic based differentiation therapy for Acute Myeloid Leukemia. Europe PMC. 2023.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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