Mesembranol

Mesembranol is an alkaloid identified in S. tortuosum with neuroinhibitory and anxiolytic-like effects. At concentrations of 17.16 and 34.32 nM, it reduces population spike amplitudes during theta burst stimulation in rat hippocampal slices. Additionally, Mesembranol (50 μM) enhances movement in the central arena in the light/dark preference test in zebrafish larvae, suggesting anxiolytic-like properties.