Avicin D
Avicin D is a plant-derived triterpenoid compound. It induces autophagy (Autophagy) through AMPK activation and inhibits the activities of mTOR and S6 kinase. Avicin D selectively triggers apoptosis (Apoptosis) and downregulates the expression of p-STAT-3, bcl-2, and Survivin. It possesses selective glucocorticoid receptor (Glucocorticoid receptor) modulation properties and inhibits the activation of NF-κB. Additionally, Avicin D exhibits antitumor effects against cutaneous T-cell lymphoma.
Product Specifications
CAS Number
197787-20-5
Smiles
C (O[C@H]1[C@H] (O[C@H]2[C@H] (O) [C@H] (O[C@@H]3O[C@H] (CO) [C@@H] (O) [C@H] (O) [C@H]3O) [C@@H] (O[C@@H]4O[C@@H] (CO) [C@H] (O) [C@H]4O) [C@H] (C) O2) [C@@H] (O) [C@H] (O) [C@@H] (CO) O1) (=O) [C@]56[C@] (C=7[C@@] (C) (C[C@H]5O) [C@@]8 (C) [C@] (CC7) ([C@]9 (C) [C@@] (CC8) (C (C) (C) [C@@H] (O[C@H]%10[C@H] (NC (C) =O) [C@@H] (O) [C@H] (O) [C@@H] (CO[C@H]%11[C@H] (O[C@H]%12[C@H] (O) [C@@H] (O) [C@H] (O) CO%12) [C@@H] (O) [C@@H] (O) [C@@H] (C) O%11) O%10) CC9) [H]) [H]) (CC (C) (C) [C@@H] (OC (/C (=C/CC[C@@] (O[C@H]%13[C@H] (O) [C@@H] (O) [C@H] (OC (/C (=C/CC[C@@] (C=C) (C) O) /CO) =O) [C@@H] (C) O%13) (C=C) C) /CO) =O) C6) [H]
Molecular Formula
C98H155NO46
Molecular Weight
2083.28
Notes
For research use only.
Available Sizes
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