7-Oxogedunin
7-Oxogedunin (Compound 7DG; Compound 16) is a small molecule that protects macrophages from pyroptosis induced by anthrax lethal toxin (LT) by targeting protein kinase R (PKR) . By inhibiting the kinase-independent functions of PKR, 7-Oxogedunin effectively suppresses the assembly of various inflammasomes (NLRP1 and NLRP3) and the activation of caspase-1. It also exhibits growth inhibitory activity against European corn borer larvae. 7-Oxogedunin is used in research focusing on LT toxicity inhibition and insecticidal studies.
Product Specifications
CAS Number
13072-74-7
Smiles
C[C@]12[C@]34[C@] (C) ([C@@H] (OC (=O) [C@]3 (O4) [H]) C=5C=COC5) CC[C@@]1 ([C@]6 (C) [C@@] (CC2=O) (C (C) (C) C (=O) C=C6) [H]) [H]
Molecular Formula
C26H30O6
Molecular Weight
438.52
Notes
For research use only.
Available Sizes
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