Mollicellin K
Mollicellin K is a benzophenone derivative isolated from Chaetomium brasiliense. It exhibits antibacterial activity against Mycobacterium tuberculosis, antimalarial activity against Plasmodium falciparum (IC50 = 1.2 μM), and antifungal activity against Candida albicans (IC50 = 1.2 μM) . Additionally, Mollicellin K demonstrates cytotoxicity towards KB cells (IC50 = 1.9 μM), BC1 cells (IC50 = 6.8 μM), NCI-H187 cells (IC50 = 0.35 μM), and five cholangiocarcinoma cell lines. The minimum inhibitory concentration (MIC) for tuberculosis is 12.5 μM.
Product Specifications
CAS Number
1179374-63-0
Smiles
O=CC1=C (O) C=C (C=2C (=O) OC=3C (OC12) =CC (O) =C (C (=O) C=C (C) C) C3C) C
Molecular Formula
C21H18O7
Molecular Weight
382.37
Notes
For research use only.
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