Monardic acid A
Monardic acid A is a selective inhibitor of AChE, with an IC50 of 53.1 μM against AChE derived from electric eels. It shows weak inhibitory activity on human erythrocyte AChE (IC50>100 μM) and has no significant effect on BChE. By inhibiting AChE activity, Monardic acid A decreases acetylcholine breakdown while also inhibiting histamine release and hyaluronidase activity, contributing to its anti-inflammatory and neurotransmitter-regulating properties. It can be isolated from lungwort (Pulmonaria officinalis) and thyme (Thymus gobicus) and is primarily used in the development of anti-inflammatory drugs and treatments for neurodegenerative diseases.
Product Specifications
CAS Number
1607436-76-9
Smiles
C (O) (=O) [C@@H]1C=2C (O[C@H]1C3=CC (O) =C (O) C=C3) =C (O) C=CC2/C=C/C (O[C@H] (CC4=CC (O) =C (O) C=C4) C (O) =O) =O
Molecular Formula
C27H22O12
Molecular Weight
538.46
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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