Anticancer agent 223
Anticancer agent 223 (Compound V-d) is an anticancer agent that triggers cell death through caspase-dependent and caspase-independent mechanisms. Anticancer agent 223 inhibits tumor spheroid formation and resensitizes cisplatin (HY-17394) -resistant A2780 cells to cisplatin (HY-17394) treatment[1].
Product Specifications
CAS Number
[1328150-75-9]
UNSPSC
12352005
Target
Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-223.html
Smiles
ClC1=CC=C(NC(C2CCN(C3=NC=NC4=C3C=CC=C4)CC2)=O)C=C1
Molecular Formula
C20H19ClN4O
Molecular Weight
366.84
References & Citations
[1]Thuy Lu Vo T, et al. Design, synthesis and biological evaluation of novel quinazoline derivatives as immune checkpoint inhibitors. Bioorg Med Chem Lett. Published online May 15, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1231511-01 0.02 mg (E-Coli)
Recombinant Mycoplasma pneumoniae Cytidine deaminase (cdd)
Ask
View Details 
MBS1231511-02 0.1 mg (E-Coli)
Recombinant Mycoplasma pneumoniae Cytidine deaminase (cdd)
Ask
View Details 
MBS1231511-03 0.02 mg (Yeast)
Recombinant Mycoplasma pneumoniae Cytidine deaminase (cdd)
Ask
View Details MBS1231511-04 0.1 mg (Yeast)
Recombinant Mycoplasma pneumoniae Cytidine deaminase (cdd)
Ask
View Details MBS1231511-05 0.02 mg (Baculovirus)
Recombinant Mycoplasma pneumoniae Cytidine deaminase (cdd)
Ask
View Details MBS1231511-06 0.02 mg (Mammalian-Cell)
Recombinant Mycoplasma pneumoniae Cytidine deaminase (cdd)
Ask
View Details