Methyllycaconitine
Methyllycaconitine (MLA) is a potent and selective α7nAChR competitive antagonist capable of crossing the blood-brain barrier. It mitigates amyloid β peptide-induced cytotoxicity in SH-SY5Y cells and prevents the effects of methamphetamine on the striatum in mice. Methyllycaconitine is employed in research on neurological disorders, such as Alzheimer's disease.
Product Specifications
CAS Number
21019-30-7
Smiles
O (C) [C@@H]1[C@@]23[C@]4 ([C@] (COC (=O) C5=C (C=CC=C5) N6C (=O) C[C@H] (C) C6=O) (CN (CC) [C@@]2 ([C@] (O) ([C@H]4OC) [C@]7 (O) [C@@]8 ([C@]3 (C[C@@] ([C@@H]8OC) ([C@@H] (OC) C7) [H]) [H]) [H]) [H]) CC1) [H]
Molecular Formula
C37H50N2O10
Molecular Weight
682.81
Notes
For research use only.
Available Sizes
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