Antcin K

Antcin K is a selective inhibitor that targets the PI3K/Akt, NF-κB, MEK1/2-ERK, p38, and AP-1 pathways. It enhances IL-10 expression, thereby suppressing pro-inflammatory cytokine production, blocking monocyte adhesion, reducing tissue damage, and promoting myogenesis. Antcin K exhibits significant anti-inflammatory, anti-damage, and tissue-protective activities. It is primarily studied in the context of inflammatory-related diseases such as periodontitis, rheumatoid arthritis, and skeletal muscle injury.