Biotin-aniline
Biotin-aniline is a probe with substantially high reactivity towards RNA and DNA. Biotin-aniline is also a novel APEX2 substrate. Biotin-aniline can label proteins via miniSOG. Biotin-aniline emerges as more efficient probe for capturing subcellular transcriptome in living cells with high spatial specificity[1][2].
Product Specifications
CAS Number
769933-15-5
UNSPSC
12352005
Target
Biochemical Assay Reagents; DNA Stain
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/biotin-aniline.html
Purity
99.63
Solubility
DMSO : ≥ 250 mg/mL
Smiles
NC(C=C1)=CC=C1CCNC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O
Molecular Formula
C18H26N4O2S
Molecular Weight
362.49
References & Citations
[1]Zhou Y, et al. Expanding APEX2 Substrates for Proximity-Dependent Labeling of Nucleic Acids and Proteins in Living Cells. Angew Chem Int Ed Engl. 2019;58 (34) :11763-11767.|[2]Zheng F, et al. Genetically encoded photocatalytic protein labeling enables spatially-resolved profiling of intracellular proteome. Nat Commun. 2023 May 23;14 (1) :2978.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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