What is the catalog number for ML213?

The catalog number for ML213 is HY-101843.

What sizes are available for ML213?

ML213 is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does ML213 come in?

ML213 is available in 6 different pack sizes.

ML213 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ML213?

ML213 is manufactured by QuantiMol.

What is the estimated delivery time for ML213?

Estimated delivery time for ML213 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ML213?

The safety data sheet for ML213 is available here: http://file.medchemexpress.com/batch_PDF/HY-101843/ML213-SDS-MedChemExpress.pdf.

ML213

ML213 is a selective activator of Kv7.2 and Kv7.4 channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively.

Product Specifications

CAS Number

489402-47-3

UNSPSC

12352005

Hazard Statement

H315, H319, H335, H413

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ML213.html

Purity

99.76

Solubility

DMSO : 36.67 mg/mL (ultrasonic)

Smiles

O=C(C1C(C2)CCC2C1)NC3=C(C)C=C(C)C=C3C

Molecular Formula

C17H23NO

Molecular Weight

257.37

Precautions

H315, H319, H335, H413

References & Citations

[1]Brueggemann LI, et al. Differential activation of vascular smooth muscle Kv7.4, Kv7.5, and Kv7.4/7.5 channels by ML213 and ICA-069673. Mol Pharmacol. 2014 Sep;86 (3) :330-41.|[2]Jepps TA, et al. Vasorelaxant effects of novel Kv 7.4 channel enhancers ML213 and NS15370. Br J Pharmacol. 2014 Oct;171 (19) :4413-24.|[3]Yu H, et al. Discovery, Synthesis, and Structure Activity Relationship of a Series of N-Aryl- bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium Channel Opener. ACS Chem Neurosci. 2011 Oct 19;2 (10) :572-577.